Today, typhoid is rare in New York City, but this disease continues to infect 17-22 million people and kill more than 500,000 people each year around the world. The majority of these cases occur in the developing world or are imported to developed countries by travelers. What tools are available to assist with typhoid control? What products are still needed to prevent, diagnose, and treat this disease? The answers to these questions and more are captured in the first quarterly update of BIO Ventures for Global Health’s (BVGH’s) Global Health Primer.